Hydrochloric Acid → HCID 54711091, compound

HRID 435825Notes

Reaction equation

HRID 435825 reaction equation
C([C:6]1[C:7](=[O:18])[NH:8][C:9]2[CH2:10][CH2:11][CH:12]([CH3:17])[CH2:13][C:14]=2[C:15]=1[OH:16])(OCC)=O.Cl>CC(O)=O>[OH:16][C:15]1[C:14]2[CH2:13][CH:12]([CH3:17])[CH2:11][CH2:10][C:9]=2[NH:8][C:7](=[O:18])[CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54711102HCID 54711102, compound

Product 1

HCID 54711091HCID 54711091, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Refluxing a suspension of 3-carboethoxy-4-hydroxy-6-methyl-5,6,7,8-tetrahydrocarbostyril (20 g; 0.08 mole) with 2N hydrochloric acid (300 ml) over 48 hrs. afforded the decarboethoxylated product isolated as in Example 1 m.p. (AcOH) > 365° C.

Workup

  1. temperatureRefluxing
  2. customafforded the decarboethoxylated product

Sources & evidence

ORD record
ord-430c67903b3b4978b922eed44380d90d
Source dataset
uspto-grants-1977_02
Patent number
US04006237

Reaction notes

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