Sodium Bicarbonate → sodium 6-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylate, hemihydrate

HRID 435858Notes

Reaction equation

HRID 435858 reaction equation
[OH:1][CH:2]([CH2:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][CH3:29])[CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8]2[O:13][C:12]([C:14]([OH:16])=[O:15])=[CH:11][C:10](=[O:17])[C:9]=2[CH:18]=1.C(=O)(O)[O-].[Na+:34]>O>[OH2:1].[OH:1][CH:2]([CH2:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][CH3:29])[CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8]2[O:13][C:12]([C:14]([O-:16])=[O:15])=[CH:11][C:10](=[O:17])[C:9]=2[CH:18]=1.[Na+:34].[Na+:34].[OH:1][CH:2]([CH2:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][CH3:29])[CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8]2[O:13][C:12]([C:14]([O-:16])=[O:15])=[CH:11][C:10](=[O:17])[C:9]=2[CH:18]=1

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 130909986-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylic acid

Product 1

HCID 131710632sodium 6-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylate, hemihydrate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 7.31 parts of 6-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylic acid and 1.54 parts of sodium bicarbonate in 100 parts of water, was heated to effect solution. The solution was filtered and freeze dried to yield 7.5 parts of sodium 6-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylate, hemihydrate.

Workup

  1. temperaturewas heated
  2. filtrationThe solution was filtered
  3. customfreeze dried

Sources & evidence

ORD record
ord-ecc1a2e391cc49ee96da688ee4da0c74
Source dataset
uspto-grants-1977_02
Patent number
US04006245

Reaction notes

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