Water → HCID 21454893, compound

Participants

Reaction Steps

To a mixture of 14g. of potassium hydroxide, 100 ml. of water and 10 ml. of ethanol was added 14g. of ethyl 2-[4-(2,2-diethoxycarbonylbutyl)phenyl]propionate and the mixture was refluxed for 6 hours. The reaction mixture was treated with the same procedure as in Example 1 (2) to give 11.1g. of a pale yellow oil. The oil was heated at 160° - 170° C. for 3 hours and subjected to vacuum distillation to give 7.2g. of the desired product boiling at 230° C./0.05 mmHg. as a colorless oil.

Provenance & Evidence