Sodium Carbonate → HCID 12671198, compound

HRID 435977Notes

Reaction equation

HRID 435977 reaction equation
Cl[C:2]1[N:7]2[N:8]=[CH:9][N:10]=[C:6]2[N:5]=[C:4]([CH3:11])[C:3]=1[CH2:12][CH2:13]Cl.[CH:15]([NH2:19])([CH2:17][CH3:18])[CH3:16].C(=O)([O-])[O-].[Na+].[Na+]>C(O)C>[CH:15]([N:19]1[C:2]2[N:7]3[N:8]=[CH:9][N:10]=[C:6]3[N:5]=[C:4]([CH3:11])[C:3]=2[CH2:12][CH2:13]1)([CH2:17][CH3:18])[CH3:16]

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 24874Sec-ButylamineHCID 36386487-chloro-6-(2-chloroethyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine

Product 1

HCID 12671198HCID 12671198, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.3g of 7-chloro-6-(2-chloroethyl)-5-methyl-s-triazolo[1,5-a]pyrimidine, 1g of sec-butylamine, 1.8g of sodium carbonate and 20 ml of ethanol was refluxed for 2 hours. The hot reaction mixture was then filtered and the filtrate was concentrated under reduced pressure.

Workup

  1. temperaturewas refluxed for 2 hours
  2. filtrationThe hot reaction mixture was then filtered
  3. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-9b201f68a2ab49968ca8a5957d493227
Source dataset
uspto-grants-1977_02
Patent number
US04007189

Reaction notes

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