Isobutylamine → HCID 12671199, compound

HRID 435978Notes

Reaction equation

HRID 435978 reaction equation
Cl[C:2]1[N:7]2[N:8]=[CH:9][N:10]=[C:6]2[N:5]=[C:4]([CH3:11])[C:3]=1[CH2:12][CH2:13]Cl.[CH2:15]([NH2:19])[CH:16]([CH3:18])[CH3:17].C(=O)([O-])[O-].[Na+].[Na+]>C(O)C>[CH2:15]([N:19]1[C:2]2[N:7]3[N:8]=[CH:9][N:10]=[C:6]3[N:5]=[C:4]([CH3:11])[C:3]=2[CH2:12][CH2:13]1)[CH:16]([CH3:18])[CH3:17]

Participants

5

Reactant 3

HCID 6558IsobutylamineHCID 10340Sodium CarbonateHCID 36386487-chloro-6-(2-chloroethyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine

Product 1

HCID 12671199HCID 12671199, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.3g of 7-chloro-6-(2-chloroethyl)-5-methyl-s-triazolo[1,5-a]pyrimidine, 1g of isobutylamine, 1.8g of sodium carbonate and 20 ml of ethanol was treated by the same manner as described in Example 3. The crystals thus obtained were recrystallized from aqueous methanol to give 1.4g of pale yellow prisms of m.p. 143° - 145° C.

Workup

  1. additionwas treated by the same manner
  2. customThe crystals thus obtained
  3. customwere recrystallized from aqueous methanol

Sources & evidence

ORD record
ord-96bae4cf2edb4213b8309f74aeed415b
Source dataset
uspto-grants-1977_02
Patent number
US04007189

Reaction notes

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