1,5-Dibromopentane → 2-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

HRID 436009Notes

Reaction equation

HRID 436009 reaction equation
C1(C2CCN(C[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]3[CH:28]([OH:29])[C:27]4[CH:30]=[CH:31][CH:32]=[C:25]5[C:26]=4[C:21](=[CH:22][CH:23]=[CH:24]5)[C:20]3=[O:33])CC=2)C=CC=CC=1.[Br:34]CCCCCBr.BrCCCCCCBr>>[Br:34][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]1[C:28](=[O:29])[C:27]2[CH:30]=[CH:31][CH:32]=[C:25]3[C:26]=2[C:21](=[CH:22][CH:23]=[CH:24]3)[C:20]1=[O:33]

Participants

4

Reactant 3

HCID 81001,5-DibromopentaneHCID 123681,6-DibromohexaneHCID 203644652-[6-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)hexyl]-2,3-dihydro-3-hydroxy-1H-benz[de]isoquinolin-1-one

Product 1

HCID 166387912-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

Procedure

Following the procedure of part (a) of example 4 but substituting 1,5-dibromopentane for the 1,6-dibromohexane, one obtains 2-(5-bromopentyl)-1H-benz[de]isoquinoline-1,3(2H)-dione; m.p. 113°-115°.

Sources & evidence

ORD record
ord-17f03022dc584da9bc4e2964e54a3f82
Source dataset
uspto-grants-1977_02
Patent number
US04007191

Reaction notes

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