Acetic Acid → 4-Nitrobenzoic Acid

Participants

Reaction Steps

600 g of p-nitrotoluene were oxidized in 2700 ml of glacial acetic acid by the method described above, in the presence of 8 g of KBr and amounts of 5 g, 10 g, 15 g, 20 g, 30 g, 40 g and 50 g of cobalt(II) acetate tetrahydrate in Examples 1 to 7, respectively. The reaction temperature was increased to 180° to 200° C after the start-up temperature was reached, and then held constant until the absorption of oxygen had ceased. The start-up temperatures and yields of the p-nitrobenzoic acid identified by the infrared spectrum are to be found in Table I.

Provenance & Evidence