Hydrochloric Acid → HCID 20096371, compound

Participants

Reaction Steps

A suspension of 314 g of 3,3-bis(4'-hydroxy-3'-methyl-phenyl) butanoic acid methyl ester (m.p. 162° C) and 80 g of sodium hydroxide in 1 liter of water was refluxed for 8 hours while stirring. After cooling to 40° -50° C the suspension was acidified with hydrochloric acid and the 3,3-bis(4'-hydroxy-3'-methylphenyl) butanoic acid was extracted with ether. The ether phase was washed several times with water and then the ether was removed in vacuo. The remaining residue was the white crystallized 3,3-bis(4'-hydroxy-3'-methylphenyl)butanoic acid, m.p. 130° C.

Provenance & Evidence