Hydrochloric Acid → HCID 9841649, compound

HRID 436187Notes

Reaction equation

HRID 436187 reaction equation
[C:1]([OH:5])(=[O:4])[CH:2]=O.[OH2:6].[C:7]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[OH:17])([CH3:10])([CH3:9])[CH3:8].Cl>C1C=CC=CC=1>[OH:17][C:12]1[CH:13]=[CH:14][C:15]([CH:2]([C:13]2[CH:14]=[CH:15][C:16]([OH:6])=[C:11]([C:7]([CH3:10])([CH3:9])[CH3:8])[CH:12]=2)[C:1]([OH:5])=[O:4])=[CH:16][C:11]=1[C:7]([CH3:10])([CH3:8])[CH3:9]

Participants

6

Reactant 4

HCID 313Hydrochloric Acid2×HCID 760Glyoxylic AcidHCID 962WaterHCID 69232-Tert-Butylphenol

Product 1

HCID 9841649HCID 9841649, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of 82 g of glyoxylic acid . 1/2 H2O (1 mol) and 375 g of o-tert.-butyl-phenol (2.5 mols) in 300 ml of benzene was saturated at 40° C wtih gaseous hydrogen chloride and condensed at this temperature. From time to time, saturation was completed by adding a small amount of gaseous hydrogen chloride. After about 40 hours, condensation was complete. The precipitate which had separated upon cooling was suction-filtered and recrystallized from methylene chloride. The yield was 190 g (52 %, calculated on glyoxylic acid), m.p. 173° C.

Workup

  1. customcondensation
  2. customThe precipitate which had separated
  3. temperatureupon cooling
  4. filtrationwas suction-filtered
  5. customrecrystallized from methylene chloride

Sources & evidence

ORD record
ord-66e4da0e880d4bed991eb8d0a0bce396
Source dataset
uspto-grants-1977_02
Patent number
US04007282

Reaction notes

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