反应详情

2-Amino-5H-s-triazolo[5,1-a]isoindole (12.08 g) and acetic anhydride (8 ml) are boiled for one hour in 150 ml of benzene. After cooling, the solid precipitate is recovered on filter and then is crystallized from ethyl acetate. Yield 14.35 g (97%). M.p. 258-9°C.

1. temperatureAfter cooling
2. customthe solid precipitate is recovered
3. filtrationon filter
4. customis crystallized from ethyl acetate