HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-Acetamido-5H-s-triazolo[5,1-a]isoindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Amino-5H-s-triazolo[5,1-a]isoindole | HCID 21455304 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2-Acetamido-5H-s-triazolo[5,1-a]isoindole | HCID 21455274 | — |
Reaction Steps
2-Amino-5H-s-triazolo[5,1-a]isoindole (12.08 g) and acetic anhydride (8 ml) are boiled for one hour in 150 ml of benzene. After cooling, the solid precipitate is recovered on filter and then is crystallized from ethyl acetate. Yield 14.35 g (97%). M.p. 258-9°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04007276 |
| Source dataset | uspto-grants-1977_02 |
| ORD ID | ord-9e37139e3025459c84c5f985bc6dacf2 |
| Source note | uspto-grants-1977_02 |