Hydrochloric Acid → HCID 21455292, compound

HRID 436197Notes

Reaction equation

HRID 436197 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[N:21]=[C:13]3[C:14]4[C:19]([CH2:20][N:12]3[N:11]=2)=[CH:18][CH:17]=[CH:16][CH:15]=4)[CH:7]=[CH:8][CH:9]=1)([O-])=O.Cl>[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([C:10]2[N:21]=[C:13]3[C:14]4[C:19]([CH2:20][N:12]3[N:11]=2)=[CH:18][CH:17]=[CH:16][CH:15]=4)[CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 2306864HCID 2306864, compound

Product 1

HCID 21455292HCID 21455292, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

2-(m-Nitrophenyl)-5H-s-triazolo[5,1-a] isoindole (7.7 g) is hydrogenated at atmospheric pressure and at room temperature in the presence of 2 g of 10% Pd on charcoal and 8 ml of 15% ethanolic hydrogen chloride. The product so obtained is purified by crystallization from ethanol. Yield 6.1 g (89%) of the title product which melts at 163-4°C.

Workup

  1. customThe product so obtained
  2. customis purified by crystallization from ethanol

Sources & evidence

ORD record
ord-c9cc0b94dc154693a624df6ed5ff5328
Source dataset
uspto-grants-1977_02
Patent number
US04007276

Reaction notes

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