Formaldehyde → HCID 21452191, compound

HRID 436389Notes

Reaction equation

HRID 436389 reaction equation
[OH:1][CH2:2][CH:3]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][C:7]2[CH2:6][CH2:5][C:4]1=2.C=O.[C:18]1(C)C=CC(S(O)(=O)=O)=CC=1>C(OC(=O)C)(=O)C.C(O)(=O)C>[C:7]123[CH2:4][CH2:5][C:6]1=[C:8]2[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:3][CH2:2][O:1][CH2:18]3

Participants

6

Reactant 3

HCID 712FormaldehydeHCID 6101p-Toluenesulfonic acidHCID 21452186HCID 21452186, compound

Product 1

HCID 21452191HCID 21452191, compound

Reagents, catalysts & solvents 2

HCID 7918Acetic AnhydrideCatalystHCID 176Acetic AcidSolvent

Procedure

A mixture of the alcohol obtained as indicated above (1 g), 0.2 g of paraformaldehyde, 0.1 g of p-toluenesulphonic acid and 10 ml of acetic acid in the presence of a few drops of acetic anhydride was heated for 41/2 hour at 95° while stirring. The usual treatments of extraction, separation, drying, and evaporation gave 0.7 g of a product which was distilled on a bulb apparatus. The purity of the thus obtained compound was of about 95 % as shown by gas chromatographic analysis. This compound was in all respects identical to that prepared in Example 1.

Workup

  1. customobtained
  2. temperaturewas heated for 41/2 hour at 95°
  3. extractionThe usual treatments of extraction, separation
  4. customdrying
  5. customevaporation

Sources & evidence

ORD record
ord-ac084e450feb4b55b051b4ad4a651673
Source dataset
uspto-grants-1977_02
Patent number
US04009127

Reaction notes

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