HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-[2-(3,5-Dimethoxy-4-hydroxybenzylidene)hydrazino]-3,4-dihydroisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Syringaldehyde | HCID 8655 | — |
| Reactant | 1-Hydrazinyl-3,4-dihydroisoquinoline | HCID 12349041 | — |
| Product | 1-[2-(3,5-Dimethoxy-4-hydroxybenzylidene)hydrazino]-3,4-dihydroisoquinoline | HCID 136002391 | — |
Reaction Steps
In a manner similar to that of Example 4, condensation of 1-hydrazino-3,4-dihydroisoquinoline (10.0 g.) and syringaldehyde (12.5 g.) and treatment of the reaction mixture with hydrochloric acid gave a solid, which was recrystallized from N,N-dimethylformamide-ether, affording 1-[2-(3,5-dimethoxy-4-hydroxybenzylidene)hydrazino]-3,4-dihydroisoquinoline (I: X=3,5-(CH3O)2 -4-HOC6H2, X'=Y=Y'=Z=Z'=H) hydrochloride in two crops (total of 18 g., m.p. 232°-233° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04009170 |
| Source dataset | uspto-grants-1977_02 |
| ORD ID | ord-fcc0816ca09341248f9561780acf4a5e |
| Source note | uspto-grants-1977_02 |