反应详情

In a manner similar to that of Example 4, condensation of 1-hydrazino-3,4-dihydroisoquinoline (10.0 g.) and syringaldehyde (12.5 g.) and treatment of the reaction mixture with hydrochloric acid gave a solid, which was recrystallized from N,N-dimethylformamide-ether, affording 1-[2-(3,5-dimethoxy-4-hydroxybenzylidene)hydrazino]-3,4-dihydroisoquinoline (I: X=3,5-(CH3O)2 -4-HOC6H2, X'=Y=Y'=Z=Z'=H) hydrochloride in two crops (total of 18 g., m.p. 232°-233° C.).

1. customgave a solid, which
2. customwas recrystallized from N,N-dimethylformamide-ether