Hydrazinium chloride → HCID 12349082, compound

HRID 436440Notes

Reaction equation

HRID 436440 reaction equation
C(O[C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH2:7][CH:6]([CH3:14])[N:5]=1)C.Cl.[NH2:16][NH2:17]>>[NH:16]([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH2:7][CH:6]([CH3:14])[N:5]=1)[NH2:17]

Participants

3

Reactant 2

HCID 115031Hydrazinium chlorideHCID 123490401-Ethoxy-3-methyl-3,4-dihydroisoquinoline

Product 1

HCID 12349082HCID 12349082, compound

Procedure

In a manner similar to that of Step B of Example 1, condensation of 1-ethoxy-3-methyl-3,4-dihydroisoquinoline (1.0 g.) and hydrazine monohydrochloride (0.36 g.) and three recrystallizations of the resulting product from ethanol-ether afforded 1-hydrazino-3-methyl-3,4-dihydroisoquinoline (V: Y=CH3, Y'= Z=Z'=H) hydrochloride (m.p. 174°-176° C.).

Sources & evidence

ORD record
ord-f4c5362be3f945a0ac1672464c83059b
Source dataset
uspto-grants-1977_02
Patent number
US04009170

Reaction notes

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