Hydrochloric Acid → HCID 70634075, compound

HRID 436513Notes

Reaction equation

HRID 436513 reaction equation
Cl.[CH3:2][N:3]([CH2:5][CH2:6][O:7][C:8]([CH:10]1[CH2:22][CH2:21][C:20]2[C:19]3[C:14](=[CH:15][CH:16]=[C:17]([Cl:23])[CH:18]=3)[NH:13][C:12]=2[CH2:11]1)=[O:9])[CH3:4].C(O)C>CCOCC>[ClH:23].[CH3:4][N:3]([CH2:5][CH2:6][O:7][C:8]([CH:10]1[CH2:22][CH2:21][C:20]2[C:19]3[C:14](=[CH:15][CH:16]=[C:17]([Cl:23])[CH:18]=3)[NH:13][C:12]=2[CH2:11]1)=[O:9])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 54353181HCID 54353181, compound

Product 1

HCID 70634075HCID 70634075, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A slight excess of 7.5N alcoholic hydrogen chloride was added to a solution of 2.7 g. of 6-chloro-1,2,3,4-tetrahydrocarbazole-2-carboxylic acid dimethylaminoethyl ester in 15 ml. of ethanol. Ether was added until crystallization was induced and the resulting precipitate was filtered and washed with a mixture of ethanol and ether. Upon drying, 2.8 g. of the salt, 6-chloro-1,2,3,4-tetrahydrocarbazole-2-carboxylic acid dimethylaminoethyl ester hydrochloride, m.p. 201°-203° , was obtained.

Workup

  1. filtrationthe resulting precipitate was filtered
  2. washwashed with a mixture of ethanol and ether
  3. customUpon drying

Sources & evidence

ORD record
ord-b97b79fc87954b51bef25c66cfd8ee68
Source dataset
uspto-grants-1977_02
Patent number
US04009181

Reaction notes

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