2-Chloroethanol → 2-Chloroethyl 2-methylpropane-1-sulfonate

HRID 436520노트

반응식

HRID 436520 반응식
[CH2:1]([Cl:4])[CH2:2][OH:3].CCOCC.[CH2:10]([S:14](Cl)(=[O:16])=[O:15])[CH:11]([CH3:13])[CH3:12]>C(N(CC)CC)C>[CH2:10]([S:14]([O:3][CH2:2][CH2:1][Cl:4])(=[O:16])=[O:15])[CH:11]([CH3:13])[CH3:12]

참가 물질

5

반응물 3

HCID 342-ChloroethanolHCID 3283Diethyl EtherHCID 1822361-Propanesulfonyl chloride, 2-methyl-

생성물 1

HCID 227699422-Chloroethyl 2-methylpropane-1-sulfonate

시약·촉매·용매 1

HCID 8471Triethylamine용매

반응 조건

온도
23 °C

실험 절차

A mixture was formed containing 6.7 ml. of ethylene chlorohydrin, 70 ml. of ether and 15.6 g. of isobutane sulfonyl chloride. Then, 14 ml. of triethylamine was added dropwise to the mixture with stirring in an ice bath over a period of 30 minutes at 12°-14° C. While stirring the mixture was allowed to warm to 23° C. (1 hour) and was then washed with water (100 ml.), dried over magnesium sulfate and evaporated to yield 19.7 g. of a colorless oil. nD30 1.4502.

후처리

  1. customA mixture was formed
  2. additioncontaining 6.7 ml
  3. stirringWhile stirring the mixture
  4. washwas then washed with water (100 ml.)
  5. dry with materialdried over magnesium sulfate
  6. customevaporated
  7. customto yield 19.7 g

출처 및 근거

ORD 기록
ord-33eaffd9f0cf4cea8556ffd18930db3e
출처 데이터셋
uspto-grants-1977_02
특허 번호
US04009191

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