Methanol → Methyl 8-(2-furyl)octanoate

HRID 436521Notes

Reaction equation

HRID 436521 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14].S(=O)(=O)(O)O.[CH3:21]O>>[CH3:21][O:14][C:13](=[O:15])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][C:2]1[O:1][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 11790484HCID 11790484, compound

Product 1

HCID 557175Methyl 8-(2-furyl)octanoate

Procedure

19 g of 8-(2-furyl)-octanoic acid were refluxed for 4 hours with 100 ml of methanol and 1.5 ml of sulphuric acid. The mixture was then evaporated to one third of its original volume. 100 g. of ice-water were then added, whereupon the mixture was extracted with ether.

Workup

  1. customThe mixture was then evaporated to one third of its original volume
  2. additionof ice-water were then added, whereupon the mixture
  3. extractionwas extracted with ether

Sources & evidence

ORD record
ord-4bd25e49329e411fa22a71789ea2e754
Source dataset
uspto-grants-1977_02
Patent number
US04009187

Reaction notes

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