8-(2,5-Dimethoxy-tetrahydro-2-furyl)-octanoic acid methyl ester → 9-Keto-12-oxo-dodecanoic acid, methyl ester

HRID 436525Notes

Reaction equation

HRID 436525 reaction equation
[CH3:1][O:2][C:3](=[O:20])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]1(OC)[CH2:15][CH2:14][CH:13]([O:16]C)[O:12]1>Cl>[CH3:1][O:2][C:3](=[O:20])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11](=[O:12])[CH2:15][CH2:14][CH:13]=[O:16]

Participants

3

Reactant 1

HCID 541867608-(2,5-Dimethoxy-tetrahydro-2-furyl)-octanoic acid methyl ester

Product 1

HCID 150938019-Keto-12-oxo-dodecanoic acid, methyl ester

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

10.0 g of the compound of step B was stirred for 30 minutes with 2100 ml of 1N hydrochloric acid at room temperature. The mixture was then extracted rapidly several times with ether.

Workup

  1. extractionThe mixture was then extracted rapidly several times with ether

Sources & evidence

ORD record
ord-24b6c66e261f407fa89e024bb3d022c9
Source dataset
uspto-grants-1977_02
Patent number
US04009187

Reaction notes

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