反应详情

349.6g (2.3 moles) of 4-amino-3-methyl-nitrobenzene were dissolved in 500g of tetrahydrofuran, 500g of acetic acid were added thereto, and 500g (3.5 moles) of acetic anhydride were added dropwise while stirring and heating at 70° to 80° C, and, after the completion of the acetic acid addition, the entire reaction system was reacted for 1 hour under reflux and then was allowed to cool whereby crystals were formed. The crystals were separated, filtered out and then dried.

1. additionwere added
2. temperatureheating at 70° to 80° C
3. customthe entire reaction system was reacted for 1 hour
4. temperatureunder reflux
5. temperatureto cool whereby crystals
6. customwere formed
7. customThe crystals were separated
8. filtrationfiltered out
9. customdried