Hydrazine hydrate (1:1) → HCID 20361207, compound

HRID 436554Notes

Reaction equation

HRID 436554 reaction equation
[CH3:1][S:2][C:3]1[CH:4]=[CH:5][C:6]2[NH:12][C:11](=S)[CH2:10][N:9]=[C:8]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[C:7]=2[CH:20]=1.O.[NH2:22][NH2:23]>CO>[CH3:1][S:2][C:3]1[CH:4]=[CH:5][C:6]2[N:12]=[C:11]([NH:22][NH2:23])[CH2:10][N:9]=[C:8]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[C:7]=2[CH:20]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20361194HCID 20361194, compound

Product 1

HCID 20361207HCID 20361207, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

According to the procedure of Preparation 1, 7-methylthio-1,3-dihydro-5-(2-pyridyl)-2H-1,4-benzodiazepine-2-thione is reacted with hydrazine hydrate in methanol to give 7-methylthio-5-(2-pyridyl)-3H-1,4-benzodiazepin-2-yl hydrazine.

Sources & evidence

ORD record
ord-ca5526655169464fa73612ac4307cdd4
Source dataset
uspto-grants-1977_02
Patent number
US04009175

Reaction notes

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