Potassium Hydroxide → N,N'-Heptamethylenebis(3,4-methylenedioxybenzamide)

HRID 436638Notes

Reaction equation

HRID 436638 reaction equation
[CH2:1]1[O:12][C:11]2[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=2[O:2]1.[CH2:13]([NH2:21])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][NH2:20].[OH-:22].[K+]>C(Cl)CCl>[CH2:1]1[O:12][C:11]2[CH:10]=[CH:9][C:5]([C:6]([NH:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][NH:21][C:6](=[O:7])[C:5]3[CH:9]=[CH:10][C:11]4[O:22][CH2:1][O:2][C:3]=4[CH:4]=3)=[O:7])=[CH:4][C:3]=2[O:2]1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 695331,7-HeptanediamineHCID 27347491,3-Benzodioxole-5-carbonyl chloride

Product 1

HCID 4132789N,N'-Heptamethylenebis(3,4-methylenedioxybenzamide)

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

m.p. 151°-152° C., 24.9 g., was prepared as in Example 1 using 3,4-methylenedioxybenzoyl chloride (prepared as in Example 6 using 30 g. of 3,4 -methylenedioxybenzoic acid) in 150 ml. of ethylene dichloride, 10.5 g. of 1,7-heptanediamine, 200 ml. of 10% aqueous potassium hydroxide solution, 500 ml. of ethylene dichloride and recrystallization from ethanol using decolorizing charcoal.

Workup

  1. customof ethylene dichloride and recrystallization from ethanol using

Sources & evidence

ORD record
ord-57bbe104ff3e4bda931143beac89bb8d
Source dataset
uspto-grants-1977_02
Patent number
US04009208

Reaction notes

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