Potassium Hydroxide → HCID 21452972, compound

HRID 436643Notes

Reaction equation

HRID 436643 reaction equation
[CH:1]1([O:7][C:8]2[CH:16]=[CH:15][C:11]([C:12](Cl)=[O:13])=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:17]([NH2:25])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][NH2:24].[OH-:26].[K+]>C(Cl)CCl>[CH:1]1([O:7][C:8]2[CH:16]=[CH:15][C:11]([C:12]([NH:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][NH:25][C:12](=[O:13])[C:11]3[CH:15]=[CH:16][C:8]([O:26][CH:1]4[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]4)=[CH:9][CH:10]=3)=[O:13])=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 695331,7-HeptanediamineHCID 21452930HCID 21452930, compound

Product 1

HCID 21452972HCID 21452972, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

m.p. 144°-145° C., 27.3 g., was prepared as in Example 1 using 4-cyclohexyloxybenzoyl chloride (from 42.0 g. of the corresponding acid as in Example 6) in 100 ml. of ethylene dichloride, 11.7 g. of 1,7-heptanediamine, 200 ml. of 10% potassium hydroxide solution, 500 ml. of ethylene dichloride and recrystallization from acetonitrile using decolorizing charcoal.

Workup

  1. customof ethylene dichloride and recrystallization from acetonitrile using

Sources & evidence

ORD record
ord-8ecfb056574b46a1968ff77015dfd94c
Source dataset
uspto-grants-1977_02
Patent number
US04009208

Reaction notes

Loading…