HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-hydroxypropan-2-one → HCID 86734825, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-hydroxypropan-2-one | HCID 11744828 | — |
| Reactant | HCID 22768402 | HCID 22768402 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86734825 | HCID 86734825 | — |
Reaction Steps
In the manner given in Example 1, 7-(trifluoromethyl)-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine in tetrahydrofuran can be treated with 1-bromo-3-hydroxypropanone under nitrogen to give 7-(trifluoromethyl)-2-[[2-bromo-1-(hydroxymethyl)ethylidene]hydrazino]-5-phenyl-3H-1,4-benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04028356 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-aa17a94ab9874fe397cac37c4b4bad7f |
| Source note | uspto-grants-1977_06 |