HCID 21431519, compound → HCID 21431512, compound

HRID 436800Notes

Reaction equation

HRID 436800 reaction equation
[CH:1]1([CH2:7][CH:8]2[CH2:13][CH2:12][CH2:11][CH2:10][N:9]2[CH2:14][CH:15]([C:17]2[CH:26]=[CH:25][C:24]3[C:19](=[CH:20][CH:21]=[C:22]([O:27]C)[CH:23]=3)[CH:18]=2)[CH3:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>Br>[CH:1]1([CH2:7][CH:8]2[CH2:13][CH2:12][CH2:11][CH2:10][N:9]2[CH2:14][CH:15]([C:17]2[CH:26]=[CH:25][C:24]3[C:19](=[CH:20][CH:21]=[C:22]([OH:27])[CH:23]=3)[CH:18]=2)[CH3:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 21431519HCID 21431519, compound

Product 1

HCID 21431512HCID 21431512, compound

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Procedure

Heating a solution of 2-cyclohexylmethyl-1-[2-(6-methoxy-2-naphthyl)-2-methylethyl]piperidine in aqueous hydrobromic acid and isolation of the product from a neutral medium affords 2-cyclohexylmethyl-1-[2-(6-hydroxy-2-naphthyl)-2-methylethyl]piperidine.

Sources & evidence

ORD record
ord-074ae85862ce44518d3b4effae302b71
Source dataset
uspto-grants-1977_06
Patent number
US04028366

Reaction notes

Loading…