Benzene, 1-isocyanato-4-nitro- → 6-Methyl-2[3-(p-nitrophenyl)ureido]-4-thiocyanatobenzothiazole

Participants

Reaction Steps

A mixture of 2-amino-6-methyl-4-thiocyanatobenzothiazole (35 g., 0.16 mole) in dimethylformamide (250ml.) was treated slowly with p-nitrophenyl isocyanate (27 g., 0.16 mole). The reaction was then heated under stirring on the steam bath for 5 hours. The mixture was then filtered hot. The solution was chilled in an ice bath and filtered. The product was combined with the solid initially filtered to give 40 g. (65%) of off-white solid.

Provenance & Evidence