反应详情

A mixture of 2-amino-6-methyl-4-thiocyanatobenzothiazole (35 g., 0.16 mole) in dimethylformamide (250ml.) was treated slowly with p-nitrophenyl isocyanate (27 g., 0.16 mole). The reaction was then heated under stirring on the steam bath for 5 hours. The mixture was then filtered hot. The solution was chilled in an ice bath and filtered. The product was combined with the solid initially filtered to give 40 g. (65%) of off-white solid.

1. temperatureThe reaction was then heated
2. filtrationThe mixture was then filtered hot
3. temperatureThe solution was chilled in an ice bath
4. filtrationfiltered
5. filtrationinitially filtered
6. customto give 40 g