HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1,3-Thiazol-2-yl)butan-1-amine → N-[1-(Methylsulfanyl)-2-nitroethenyl]-4-(1,3-thiazol-2-yl)butan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1,3-Thiazol-2-yl)butan-1-amine | HCID 17931257 | — |
| Reactant | 1-Nitro2-methylthio-2-methylsulphinylethylene | HCID 54487094 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[1-(Methylsulfanyl)-2-nitroethenyl]-4-(1,3-thiazol-2-yl)butan-1-amine | HCID 71391849 | — |
Reaction Steps
A solution of 2-(4-aminobutyl)thiazole (1.56 g) in methanol (35 ml) was added dropwise over 30 minutes to a stirred solution of 1-methylsulphinyl-1-methylthio -2-nitroethylene (1.81 g) in methanol (60 ml). The product was isolated as in the previous Examples and recrystallised from isopropanol to give the title product, m.p. 75.5°-76°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04028379 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-099572d981be4a4e8526a74035aaf758 |
| Source note | uspto-grants-1977_06 |