反应详情

A suspension of 19.7 g of the product of Step A in 100 ml of acetone containing 200 ml of 0.1N hydrochloric acid was stirred at room temperature for 17 hours and the acetone was then evaporated under reduced pressure. The mixture was then extracted with methylene chloride and the organic solution was washed with aqueous sodium bicarbonate solution, then with water, dried over sodium sulfate and evaporated to dryness to obtain 15.7 g of 10-methyl-6-oxa-9-undecene-2-one in the form of a colorless liquid used as is for the next step.

1. customthe acetone was then evaporated under reduced pressure
2. extractionThe mixture was then extracted with methylene chloride
3. washthe organic solution was washed with aqueous sodium bicarbonate solution
4. dry with materialwith water, dried over sodium sulfate
5. customevaporated to dryness