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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 436883Generated: October 28, 2026

Quinoline → 3,7,11-Trimethyldodeca-1,6,10-trien-3-ol

https://huagongshe.com/reaction/436883

Reaction equation

Participants

RoleNameHCIDCharge
ReactantQuinolineHCID 7047—
Reactant3,7,11-Trimethyldodeca-6,10-dien-1-yn-3-olHCID 5365823—
CatalystPd Lindlar catalystHCID 131710810—
SolventHexaneHCID 8058—
Product3,7,11-Trimethyldodeca-1,6,10-trien-3-olHCID 888890.6%

Reaction Steps

Further, 0.5 ml of quinoline and 20 g of 0.25% Pd-Lindlar catalyst was added in a solution of 1,280 g of the said dehydronerolidol in 2,000 ml of n-hexane and the mixture was hydrogenated at room temperature and normal pressure. After post-treatment, the reaction mixture was subjected to vacuum distillation to give 1,170 g of nerolidol having b.p. 105° - 110° C. (0.5 mmHg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04028385
Source datasetuspto-grants-1977_06
ORD IDord-7d45f6fc1930445095d4e703d19bd850
Source noteuspto-grants-1977_06