HuagongsheHuagongshe Chemistry Print Report · For research reference only
Quinoline → 3,7,11-Trimethyldodeca-1,6,10-trien-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Quinoline | HCID 7047 | — |
| Reactant | 3,7,11-Trimethyldodeca-6,10-dien-1-yn-3-ol | HCID 5365823 | — |
| Catalyst | Pd Lindlar catalyst | HCID 131710810 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 3,7,11-Trimethyldodeca-1,6,10-trien-3-ol | HCID 8888 | 90.6% |
Reaction Steps
Further, 0.5 ml of quinoline and 20 g of 0.25% Pd-Lindlar catalyst was added in a solution of 1,280 g of the said dehydronerolidol in 2,000 ml of n-hexane and the mixture was hydrogenated at room temperature and normal pressure. After post-treatment, the reaction mixture was subjected to vacuum distillation to give 1,170 g of nerolidol having b.p. 105° - 110° C. (0.5 mmHg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04028385 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-7d45f6fc1930445095d4e703d19bd850 |
| Source note | uspto-grants-1977_06 |