Methyl iodide → HCID 85857780, compound

HRID 436897Notes

Reaction equation

HRID 436897 reaction equation
[CH2:1]1[O:27][C:4]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[F:26])([C:5]2[C:10]([CH2:11]SC3C=CC=CC=3)=[CH:9][CH:8]=[C:7]([Cl:19])[CH:6]=2)[O:3][CH2:2]1.C[I:29]>>[CH2:1]1[O:27][C:4]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[F:26])([C:5]2[C:10]([CH2:11][I:29])=[CH:9][CH:8]=[C:7]([Cl:19])[CH:6]=2)[O:3][CH2:2]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 86733072HCID 86733072, compound

Product 1

HCID 85857780HCID 85857780, compound

Procedure

The starting material is obtained as follows: The solution of 10 g of 3-chloro-2'-fluoro-6-phenylmercaptomethyl-benzophenone ethylene ketal (Example 2) in 50 ml of methyl iodide is refluxed under nitrogen for 5 days. It is evaporated and the formed methyl phenyl thioether distilled off at 60°/0.1 mm Hg, to yield the 3-chloro-2'-fluoro-6-iodomethyl-benzophenone ethylene ketal.

Workup

  1. customThe starting material is obtained
  2. customIt is evaporated
  3. distillationthe formed methyl phenyl thioether distilled off at 60°/0.1 mm Hg

Sources & evidence

ORD record
ord-ae71c85eaa9b4709a3b64cab8c8416e0
Source dataset
uspto-grants-1977_06
Patent number
US04028381

Reaction notes

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