反应详情

A mixture of tetrachloropyrazine (10.8 g, 0.05 mol), methylaminoethanol (3.7 g, 0.05 mol), and triethylamine (10 g, 0.1 mol) was stirred overnight at room temperature. The white solid was filtered out and the filtrate concentrated on the rotary evaporator to leave a yellow oil. This was distilled on a Kugelrohr apparatus to give 10 g (78% of theoretical yield) of a yellow oil (b.p. 110° at 0.05 mm Hg).

1. filtrationThe white solid was filtered out
2. concentrationthe filtrate concentrated on the rotary evaporator
3. customto leave a yellow oil
4. distillationThis was distilled on a Kugelrohr apparatus
5. customto give
6. custom10 g (78% of theoretical yield) of a yellow oil (b.p. 110° at 0.05 mm Hg)