反应详情

To the t-butoxycarbonylalanylprolyl-2-azaalanine ethyl ester obtained above is added 15 ml of methylene chloride. The reaction mixture is cooled to 0° and 15 ml of trifluoroacetic acid added. After stirring for 1 hour at 0° and 1 hour at room temperature, the reaction mixture is concentrated in vacuo to yield alanylprolyl-2-azaalanine ethyl ester as its trifluoroacetic acid salt.

1. temperatureThe reaction mixture is cooled to 0°
2. concentrationthe reaction mixture is concentrated in vacuo