p-Toluenesulfonyl isocyanate → HCID 73793272, compound

HRID 437135Notes

Reaction equation

HRID 437135 reaction equation
[CH3:1][N:2]1[CH2:6][CH2:5][NH:4][C:3]1=[CH:7][N+:8]([O-:10])=[O:9].[C:11]1([CH3:23])[CH:16]=[CH:15][C:14]([S:17]([N:20]=[C:21]=[O:22])(=[O:19])=[O:18])=[CH:13][CH:12]=1>C(Cl)Cl.CCOCC>[CH3:1][N:2]1[CH2:6][CH2:5][NH:4][C:3]1=[C:7]([N+:8]([O-:10])=[O:9])[C:21]([NH:20][S:17]([C:14]1[CH:15]=[CH:16][C:11]([CH3:23])=[CH:12][CH:13]=1)(=[O:19])=[O:18])=[O:22]

Participants

5

Reactant 2

HCID 77703p-Toluenesulfonyl isocyanateHCID 702500461-Methyl-2-(nitromethylidene)imidazolidine

Product 1

HCID 73793272HCID 73793272, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

A solution of 1.43 g of 1A in 20 ml of methylene chloride was treated with 1.99 g of p-tolylsulfonyl isocyanate at room temperature. After a brief period of exothermicity, the mixture was held at room temperature overnight. The mixture then was diluted with 20 ml of dry ether and filtered to give 1, as a white powder, m.p.: 155°- 157°.

Workup

  1. waitAfter a brief period of exothermicity
  2. filtrationfiltered
  3. customto give 1

Sources & evidence

ORD record
ord-10e56aaaa9d1481b8e547b577aaf8584
Source dataset
uspto-grants-1977_06
Patent number
US04029791

Reaction notes

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