HCID 21430523, compound → HCID 21430509, compound

Participants

Reaction Steps

A suspension of the thiourea prepared above (0.4 g) in ethanol (50 ml.) was stirred under reflux conditions (78°) with mercuric oxide (0.5 g) for 4 hours and filtered while hot. Evaporation of the filtrate yielded a white solid which was recrystallised from ethanol to give 0.1 g of 8-chloro-7-(2-imidazolin-2-ylamino)-4-methoxyquinazoline as a free base, m.p. 238°-239°.

Provenance & Evidence