Benzyl Alcohol → HCID 21430450, compound

HRID 437158Notes

Reaction equation

HRID 437158 reaction equation
Cl.[CH3:2][N:3]([CH3:23])[S:4]([C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][C:15]=1[N:16]1[CH2:21][CH2:20][N:19]([CH3:22])[CH2:18][CH2:17]1)[C:10]([Cl:12])=[O:11])(=[O:6])=[O:5].C(N(CC)CC)C.[CH2:31]([OH:38])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[ClH:12].[CH2:31]([O:38][C:10](=[O:11])[C:9]1[CH:13]=[CH:14][C:15]([N:16]2[CH2:21][CH2:20][N:19]([CH3:22])[CH2:18][CH2:17]2)=[C:7]([S:4](=[O:5])(=[O:6])[N:3]([CH3:23])[CH3:2])[CH:8]=1)[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1

Participants

4

Reactant 3

HCID 244Benzyl AlcoholHCID 8471TriethylamineHCID 21430472HCID 21430472, compound

Product 1

HCID 21430450HCID 21430450, compound

Procedure

40 Grams of 3-dimethylsulfamoyl-4-(4-methylpiperazine-1-yl)-benzoylchloride-hydrochloride (0.1 mole) were dissolved in 0.5 l of benzyl alcohol. 50 Milliliters of triethylamine were added dropwise to the solution, while stirring at room temperature. The mixture was then heated for 10 minutes on the steam bath and was subsequently evaporated in vacuo.

Workup

  1. temperatureThe mixture was then heated for 10 minutes on the steam bath
  2. customwas subsequently evaporated in vacuo

Sources & evidence

ORD record
ord-a3da6e9ce0994b22a7cc01449b3e71fc
Source dataset
uspto-grants-1977_06
Patent number
US04029787

Reaction notes

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