Hydrochloric Acid → HCID 21430479, compound

Participants

Reaction Conditions

Reaction Steps

29 Grams of 4-chloro-3-diethylsulfamoyl-benzoic acid were heated with 30 g of N-methylpiperazine for 4 hours at 140° C. Subsequently the reaction solution, which had cooled down to 80° C., was introduced into 0.4 l of water, and the solution was neutralized with 5N HCl. As soon as the precipitate, which was amorphous at first, became crystallized, it was suction-filtered and recrystallized from methanol.

Provenance & Evidence