HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21430447, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 3-(Aminosulfonyl)-4-chloro-N-methyl-N-(phenylmethyl)benzamide | HCID 21430456 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 21430447 | HCID 21430447 | — |
Reaction Steps
33.8 Grams of 4-chloro-3-sulfamoylbenzoic acid-N-methylbenzylamide (0.1 mole) were heated with 80 ml of N-methylpiperazine for 4 hours under reflux. Subsequently the solution was introduced into 0.4 l of water, the pH value of the mixture was adjusted to 9.0 by means of glacial acetic acid, and the mixture was then allowed to stand for 2 days at room temperature. The crystalline precipitate was separated and was recrystallized from a mixture of ethanol and water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04029787 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-1bf4827eb3854977b6883316797887c1 |
| Source note | uspto-grants-1977_06 |