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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 437215Generated: October 30, 2026

Hydrochloric Acid → 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(2-chlorobenzamido)-piperidine

https://huagongshe.com/reaction/437215

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantN-{1-[2-(3,4-dimethoxyphenyl)ethyl]-4-piperidinyl}benzamideHCID 21413257—
Product1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(2-chlorobenzamido)-piperidineHCID 21430616—

Reaction Steps

The title compound as its hydrochloride (m.p. 250°-2° C.) was prepared in the same way as for the compound of Example 5 but using o-chlorobenzoyl chloride in place of benzoyl chloride. (Found: C, 60.2; H, 6.1; N, 6.3. C22H26Cl N2O3.HCl requires C, 60.3; H, 6.2; N, 6.4%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04029801
Source datasetuspto-grants-1977_06
ORD IDord-96fdf89f768941adb6621716c504411f
Source noteuspto-grants-1977_06