HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Benzodioxole-5-carbonyl chloride → 2-(3,4-Dimethoxyphenyl)ethyl-4-piperonylamidopiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Benzodioxole-5-carbonyl chloride | HCID 2734749 | — |
| Reactant | N-{1-[2-(3,4-dimethoxyphenyl)ethyl]-4-piperidinyl}benzamide | HCID 21413257 | — |
| Product | 2-(3,4-Dimethoxyphenyl)ethyl-4-piperonylamidopiperidine | HCID 21430636 | — |
| Product | Dihydrate;hydrochloride | HCID 21899424 | — |
Reaction Steps
The title compound hydrochloride dihydrate (m.p. 285°-8° C.) was prepared in the same way as for the compound of Example 5 but utilising piperonyloyl chloride in place of benzoyl chloride. (Found: C, 57.1; H, 6.8; N, 5.7. C23H28N2O5.HCl.2H2O requires C, 57.0; H, 6.8; N, 5.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04029801 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-4cb6a7e44a744ce4b2922d4502196685 |
| Source note | uspto-grants-1977_06 |