HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzoyl chloride → HCID 21430572, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzoyl chloride | HCID 8501 | — |
| Reactant | 4-Amino-1-(4-phenyl-4-oxobutyl)piperidine dihydrochloride | HCID 22754837 | — |
| Product | HCID 21430572 | HCID 21430572 | — |
Reaction Steps
4-Amino-1-(4-phenyl-4-oxobutyl)piperidine dihydrochloride (3.19 g.) was acylated with p-chloro-benzoyl chloride (1.75 g.) in the manner of example 75. Filtration afforded the title compound as the base (3.277 g.). This was suspended in boiling ethanol (15 ml.) and ethanol/HCl added until acid. On cooling the title compound crystallised out as the hydrochloride, colourless needles (3.41 g.), m.p. 261.1°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04029801 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-dfb1251c2f844c06abe63080ec5f6acc |
| Source note | uspto-grants-1977_06 |