反应详情

1-(Chlorobenzoyl)-2-(4-aminophenyl)hydrazine hydrochloride (2.0 g, 0.0067 mole) was mixed with ethanol (125 ml) and water (25 ml). Phenyl isothiocyanate (1.1 g, 0.01 mole) was added to the mixture along with sodium acetate (0.82 g, 0.01 mole) in water (10 ml). The reaction mixture was stirred and refluxed for 5 minutes, then was stirred at room temperature for one and one half hours. The mixture was chilled in ice and then filtered. The product was washed with ethanol and dried to give an off-white solid. Yield 1.9 g (71%), m.p. 197.5°-199° C.

1. temperaturerefluxed for 5 minutes
2. stirringwas stirred at room temperature for one and one half hours
3. temperatureThe mixture was chilled in ice
4. filtrationfiltered
5. washThe product was washed with ethanol
6. customdried
7. customto give an off-white solid