反应详情

1-Acetyl-2-(4-benzylaminophenyl)hydrazine (2.80 g, 0.011 mole) and phenylisothiocyanate (1.35 g, 0.01 mole) were mixed in ethanol (25 ml) and the resulting mixture was refluxed for 5 minutes. The mixture was chilled in ice and water was added to precipitate the product. The product oiled out of solution, but became crystalline upon standing and scratching. The solid was filtered off and washed with water, then ether. After drying the product was a pale yellow crystalline powder. Yield 3.0 g (77%), m.p. 114°-117° C.

1. temperaturethe resulting mixture was refluxed for 5 minutes
2. temperatureThe mixture was chilled in ice
3. customto precipitate the product
4. filtrationThe solid was filtered off
5. washwashed with water
6. customAfter drying the product