Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | HCID 54711092 | HCID 54711092 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 54711103 | HCID 54711103 | — |
Reaction Steps
A suspension of 1-ethyl-4-hydroxy-5,6,7,8-tetrahydrocarbostyril (1.74 g; 0.009 mole) in glacial acetic acid (10 ml) was solubilised with concentrated nitric acid (2.5 ml; d 1.42) and the mixture heated for a few minutes at 100° C. After cooling and dilution with water a yellow crystalline solid separated. On recrystallisation from ethanol it had m.p. 152°- 154° C (d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04031099 |
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| Source dataset | uspto-grants-1977_06 |
|---|
| ORD ID | ord-78fb1970f3594e1fb004854afe4ea621 |
|---|
| Source note | uspto-grants-1977_06 |
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