Hydrochloric Acid → HCID 20309702, compound

HRID 437374Notes

Reaction equation

HRID 437374 reaction equation
[C:1]1(=[O:20])[N:6]([C:7]2[CH:8]=[C:9]([CH:13]=[C:14]([N+:16]([O-:18])=[O:17])[CH:15]=2)[C:10]([OH:12])=[O:11])[C:5](=[O:19])[CH2:4][CH2:3][CH2:2]1.Cl.[OH-:22].[Na+]>>[C:10]([C:9]1[CH:8]=[C:7]([CH:15]=[C:14]([N+:16]([O-:18])=[O:17])[CH:13]=1)[NH:6][C:5](=[O:19])[CH2:4][CH2:3][CH2:2][C:1]([OH:20])=[O:22])([OH:12])=[O:11]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 20309632HCID 20309632, compound

Product 1

HCID 20309702HCID 20309702, compound

Procedure

3'-Carboxy-5'-nitroglutaranilic Acid [F; Y is CH2CH2CH2, Z is OH] was prepared by warming gently a solution of 5.0 g. of 3-glutarimido-5-nitrobenzoic acid in excess 10% aqueous sodium hydroxide. The solution was acidified with 3N hydrochloric acid and the product collected and recrystallized from ethyl acetate to give 3'-carboxy-5'-nitroglutaranilic acid, pale yellow prisms, m.p. 182°-184° C.

Workup

  1. custom3'-Carboxy-5'-nitroglutaranilic Acid [F; Y is CH2CH2CH2, Z is OH] was prepared
  2. temperatureby warming gently a solution of 5.0 g
  3. customthe product collected
  4. customrecrystallized from ethyl acetate

Sources & evidence

ORD record
ord-1b6da9ec6d134af8b1bad7ac9443ad2e
Source dataset
uspto-grants-1977_06
Patent number
US04031088

Reaction notes

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