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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 437390Generated: October 30, 2026

2,6-Diaminopyridine → 5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-amine

https://huagongshe.com/reaction/437390

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DiaminopyridineHCID 8861—
ReactantHexafluoroacetylacetoneHCID 73706—
Product5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-amineHCID 2783071—

Reaction Steps

A process as claimed in claim 1 wherein 2,6-diaminopyridine is reacted with 1,1,1,5,5,5-hexafluoroacetylacetone to provide 2-amino-5,7-di(trifluoromethyl)-1,8-naphthyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04031103
Source datasetuspto-grants-1977_06
ORD IDord-9783d5eaa771445ab36ce86c1e0c6c74
Source noteuspto-grants-1977_06