Iodoethane → HCID 20360307, compound

HRID 437422Notes

Reaction equation

HRID 437422 reaction equation
[C:1]([C:5]1[CH:13]=[C:9]([C:10]([NH2:12])=[O:11])[C:8]([OH:14])=[CH:7][CH:6]=1)([O:3][CH3:4])=[O:2].I[CH2:16][CH3:17].C[O-].[Na+].C(OC1C=CC(OC)=CC=1C(N)=O)C>CO>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([O:14][CH2:16][CH3:17])=[C:9]([CH:13]=1)[C:10]([NH2:12])=[O:11])([O:3][CH3:4])=[O:2]

Participants

6

Reactant 4

HCID 6340IodoethaneHCID 10607886Benzoic acid, 3-(aminocarbonyl)-4-hydroxy-, methyl esterHCID 10942334Sodium MethoxideHCID 20360292HCID 20360292, compound

Product 1

HCID 20360307HCID 20360307, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

5-Carbomethoxy-2-ethoxybenzamide (m.p. 159°-161°) was prepared from 5-carbomethoxysalicylamide, iodoethane, and sodium methoxide in methanol in a manner analogous to that described for the preparation of 2-ethoxy-5-methoxybenzamide in Preparation 14A.

Sources & evidence

ORD record
ord-32b723deb57248088e6c451c97fde23d
Source dataset
uspto-grants-1977_06
Patent number
US04031093

Reaction notes

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