HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 12535843, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 12535800 | HCID 12535800 | — |
| Product | HCID 12535843 | HCID 12535843 | 100.2% |
Reaction Steps
A solution of ethyl 1,6-dihydro-6-oxo-2-(2-ethoxyphenyl)pyrimidine-5-carboxylate (2 g., 6.9 mmole) in 1N NaOH (20 ml., 20 mmole) was heated at reflux for 10 minutes. The solution was cooled and acidified with 6N HCl to yield the title product (1.8 g., m.p. 168°-184°). Recrystallization from acetonitrile gave 1.2 g. of colorless crystals, m.p. 186°-188°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04031093 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-ce4c3b87b1b94626854d964a88691da3 |
| Source note | uspto-grants-1977_06 |