Hydrochloric Acid → HCID 12535845, compound

Participants

Reaction Steps

A solution of ethyl 1,6-dihydro-6-oxo-2-(2-isopropoxyphenyl)pyrimidine-5-carboxylate (3.02 g.) in 1N NaOH (25 ml.) was heated on a steam bath for 15 minutes. The solution was acidified with 1N HCl (26 ml.) to precipitate 2.7 g. of the title acid, m.p. 191°-193°. Recrystallization from methanol gave pale yellow crystals of the acid, m.p. 193°-195°.

Provenance & Evidence